# OnCo record paper-keynote-042-tmb-mutations-ann-oncol-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-keynote-042-tmb-mutations-ann-oncol-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-keynote-042-tmb-mutations-ann-oncol-2023" ;
  schema:name "Associations of tissue tumour mutational burden and mutational status with clinical outcomes in KEYNOTE-042"@en ;
  schema:description "In a large randomised trial of immunotherapy given alone, patients whose tumours carried more mutations did better on the drug than on chemotherapy, and patients with fewer mutations did not."@en ;
  schema:url <https://onco.cc/key-papers/paper-keynote-042-tmb-mutations-ann-oncol-2023/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.annonc.2023.01.011>, <https://pubmed.ncbi.nlm.nih.gov/36709038/> ;
  schema:sameAs <https://doi.org/10.1016/j.annonc.2023.01.011> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "Mok TSK, Lopes G, Cho BC, et al." ;
  onco:related <https://onco.cc/biomarkers/tmb-high/>, <https://onco.cc/biomarkers/pd-l1-tps/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:technologies <https://onco.cc/technologies/tmb-testing/>, <https://onco.cc/technologies/wes-wgs/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/pdl1/>, <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/stk11/>, <https://onco.cc/targets/keap1/>, <https://onco.cc/targets/kras/> ;
  onco:drugs <https://onco.cc/drugs/pembrolizumab/> ;
  onco:pathways <https://onco.cc/pathways/pd1-checkpoint/>, <https://onco.cc/pathways/cancer-immunity-cycle/> ;
  onco:terms <https://onco.cc/terms/tmb/>, <https://onco.cc/terms/stk11-keap1/> ;
  onco:people <https://onco.cc/people/tony-mok/> ;
  onco:journals <https://onco.cc/journals/annals-of-oncology/> .