# OnCo record paper-keynote-522-nejm-2022 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-keynote-522-nejm-2022/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-keynote-522-nejm-2022" ;
  schema:name "KEYNOTE-522: adding pembrolizumab before and after surgery in early triple-negative breast cancer"@en ;
  schema:description "Adding the immunotherapy pembrolizumab to chemotherapy before surgery, then continuing it afterwards, cut the risk of relapse or death by about a third in stage II-III triple-negative breast cancer and later improved survival."@en ;
  schema:url <https://onco.cc/key-papers/paper-keynote-522-nejm-2022/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2112651>, <https://doi.org/10.1056/NEJMoa1910549>, <https://clinicaltrials.gov/study/NCT03036488> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa2112651> ;
  schema:datePublished "2022"^^xsd:gYear ;
  schema:author "Schmid P, Cortes J, Dent R, et al." ;
  onco:related <https://onco.cc/ideas/idea-post-neoadjuvant-adc/>, <https://onco.cc/ideas/idea-ctdna-escalation-tnbc/> ;
  onco:cancers <https://onco.cc/cancers/tnbc/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/platinum/> ;
  onco:targets <https://onco.cc/targets/pd1/> ;
  onco:drugs <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/> ;
  onco:companies <https://onco.cc/companies/merck/> ;
  onco:terms <https://onco.cc/terms/pcr/>, <https://onco.cc/terms/efs/>, <https://onco.cc/terms/neoadjuvant-adjuvant/>, <https://onco.cc/terms/cps/>, <https://onco.cc/terms/irae/>, <https://onco.cc/terms/rcb/> ;
  onco:trials <https://onco.cc/trials/keynote-522/> ;
  onco:people <https://onco.cc/people/javier-cortes/>, <https://onco.cc/people/jonas-bergh/>, <https://onco.cc/people/park-yeon-hee/>, <https://onco.cc/people/carsten-denkert/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-immunotherapy-response/>, <https://onco.cc/bottlenecks/b-toxicity-qol/>, <https://onco.cc/bottlenecks/b-dormancy-mrd/> ;
  onco:journals <https://onco.cc/journals/nejm/> .