# OnCo record paper-keynote-689-nejm-2025 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-keynote-689-nejm-2025/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-keynote-689-nejm-2025" ;
  schema:name "KEYNOTE-689: neoadjuvant and adjuvant pembrolizumab for resectable locally advanced head and neck cancer"@en ;
  schema:description "Giving pembrolizumab before surgery and continuing it afterwards alongside radiotherapy reduced recurrences in resectable locally advanced head and neck cancer, the first improvement in surgical treatment of the disease in two decades."@en ;
  schema:url <https://onco.cc/key-papers/paper-keynote-689-nejm-2025/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2415434>, <https://pubmed.ncbi.nlm.nih.gov/40532178/> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa2415434> ;
  schema:datePublished "2025"^^xsd:gYear ;
  schema:author "Uppaluri R, Haddad RI, Tao Y, et al." ;
  onco:cancers <https://onco.cc/cancers/hpv-negative-head-and-neck-cancer/> ;
  onco:drugs <https://onco.cc/drugs/pembrolizumab/> ;
  onco:trials <https://onco.cc/trials/keynote-689/> ;
  onco:journals <https://onco.cc/journals/nejm/> .