# OnCo record paper-klein-ccga3-mced-validation-ann-oncol-2021 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-klein-ccga3-mced-validation-ann-oncol-2021/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-klein-ccga3-mced-validation-ann-oncol-2021" ;
  schema:name "Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set"@en ;
  schema:description "The methylation blood test now sold as Galleri detected half of all cancers and one in six stage I cancers in 4,077 people, while wrongly flagging one healthy person in 200, and named the organ correctly in 89% of positives."@en ;
  schema:url <https://onco.cc/key-papers/paper-klein-ccga3-mced-validation-ann-oncol-2021/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.annonc.2021.05.806>, <https://pubmed.ncbi.nlm.nih.gov/34176681/> ;
  schema:sameAs <https://doi.org/10.1016/j.annonc.2021.05.806> ;
  schema:datePublished "2021"^^xsd:gYear ;
  schema:author "Klein EA, Richards D, Cohn A, et al." ;
  onco:cancers <https://onco.cc/cancers/pancreatic/> ;
  onco:technologies <https://onco.cc/technologies/mced/>, <https://onco.cc/technologies/cfdna-methylation-testing/>, <https://onco.cc/technologies/methylation-profiling/>, <https://onco.cc/technologies/liquid-biopsy/> ;
  onco:drugs <https://onco.cc/drugs/galleri/> ;
  onco:companies <https://onco.cc/companies/grail/> ;
  onco:terms <https://onco.cc/terms/cfdna/>, <https://onco.cc/terms/ctdna/> ;
  onco:journals <https://onco.cc/journals/annals-of-oncology/> .