# OnCo record paper-lee-clonal-history-small-cell-transformation-jco-2017 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-lee-clonal-history-small-cell-transformation-jco-2017/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-lee-clonal-history-small-cell-transformation-jco-2017" ;
  schema:name "Clonal history and genetic predictors of transformation into small-cell carcinomas from lung adenocarcinomas"@en ;
  schema:description "Some lung cancers escape a targeted pill by changing into a different kind of cancer. Reading whole genomes from the same patients over time showed the change was set up from the beginning, in tumours that had already lost two particular genes."@en ;
  schema:url <https://onco.cc/key-papers/paper-lee-clonal-history-small-cell-transformation-jco-2017/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.2016.71.9096>, <https://pubmed.ncbi.nlm.nih.gov/28498782/> ;
  schema:sameAs <https://doi.org/10.1200/JCO.2016.71.9096> ;
  schema:datePublished "2017"^^xsd:gYear ;
  schema:author "Lee JK, Lee J, Kim S, et al." ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/sclc/> ;
  onco:technologies <https://onco.cc/technologies/wes-wgs/>, <https://onco.cc/technologies/histopathology-ihc/> ;
  onco:targets <https://onco.cc/targets/egfr/>, <https://onco.cc/targets/rb1/>, <https://onco.cc/targets/tp53/> ;
  onco:pathways <https://onco.cc/pathways/lineage-plasticity-neuroendocrine/>, <https://onco.cc/pathways/clonal-evolution/>, <https://onco.cc/pathways/resistance-routes-map/>, <https://onco.cc/pathways/mutagenesis-signatures/> ;
  onco:terms <https://onco.cc/terms/histologic-transformation/>, <https://onco.cc/terms/resistance/>, <https://onco.cc/terms/mutational-signature/>, <https://onco.cc/terms/ihc/> ;
  onco:journals <https://onco.cc/journals/jco/> .