# OnCo record paper-loree-tumour-location-continuum-colorectal-ccr-2018 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-loree-tumour-location-continuum-colorectal-ccr-2018/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-loree-tumour-location-continuum-colorectal-ccr-2018" ;
  schema:name "Classifying colorectal cancer by tumor location rather than sidedness highlights a continuum in mutation profiles and consensus molecular subtypes"@en ;
  schema:description "The left-right split is a convenient line but the bowel is a gradient. Mutation rates change continuously from caecum to rectum, and the sigmoid-rectal region and the transverse colon do not fit the convention."@en ;
  schema:url <https://onco.cc/key-papers/paper-loree-tumour-location-continuum-colorectal-ccr-2018/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1158/1078-0432.CCR-17-2484>, <https://pubmed.ncbi.nlm.nih.gov/29180604/> ;
  schema:sameAs <https://doi.org/10.1158/1078-0432.CCR-17-2484> ;
  schema:datePublished "2018"^^xsd:gYear ;
  schema:author "Loree JM, Pereira AAL, Lam M, et al." ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:targets <https://onco.cc/targets/kras/>, <https://onco.cc/targets/braf/>, <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/pik3ca/>, <https://onco.cc/targets/smad4/>, <https://onco.cc/targets/ctnnb1/>, <https://onco.cc/targets/gnas/>, <https://onco.cc/targets/pten/> ;
  onco:institutions <https://onco.cc/institutions/md-anderson/> ;
  onco:terms <https://onco.cc/terms/sidedness/>, <https://onco.cc/terms/cms-subtypes/> ;
  onco:journals <https://onco.cc/journals/clinical-cancer-research/> .