# OnCo record paper-martuza-engineered-hsv-glioma-science-1991 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
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<https://onco.cc/key-papers/paper-martuza-engineered-hsv-glioma-science-1991/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-martuza-engineered-hsv-glioma-science-1991" ;
  schema:name "Martuza 1991: the first genetically engineered virus built to treat a cancer"@en ;
  schema:description "A herpes virus was deliberately crippled so that it could only multiply in dividing cells, injected into human brain tumours growing in mice, and it made the mice live longer."@en ;
  schema:url <https://onco.cc/key-papers/paper-martuza-engineered-hsv-glioma-science-1991/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1126/science.1851332>, <https://pubmed.ncbi.nlm.nih.gov/1851332/> ;
  schema:sameAs <https://doi.org/10.1126/science.1851332> ;
  schema:datePublished "1991"^^xsd:gYear ;
  schema:author "Martuza RL, Malick A, Markert JM, Ruffner KL, Coen DM" ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/> ;
  onco:sections <https://onco.cc/fronts/immunotherapy/> ;
  onco:technologies <https://onco.cc/technologies/oncolytic-virus/> ;
  onco:people <https://onco.cc/people/robert-martuza/> ;
  onco:journals <https://onco.cc/journals/science/> .