# OnCo record paper-mcgrail-tmb-pan-cancer-response-ann-oncol-2021 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-mcgrail-tmb-pan-cancer-response-ann-oncol-2021/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-mcgrail-tmb-pan-cancer-response-ann-oncol-2021" ;
  schema:name "High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types"@en ;
  schema:description "Pooling more than 10,000 tumours, a high mutation count predicted response to immunotherapy in melanoma, lung and bladder cancers but not in breast, prostate or brain tumours."@en ;
  schema:url <https://onco.cc/key-papers/paper-mcgrail-tmb-pan-cancer-response-ann-oncol-2021/> ;
  schema:dateModified "2026-10-20"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.annonc.2021.02.006>, <https://pubmed.ncbi.nlm.nih.gov/33736924/> ;
  onco:tag "precision" ;
  schema:sameAs <https://doi.org/10.1016/j.annonc.2021.02.006> ;
  schema:datePublished "2021"^^xsd:gYear ;
  schema:author "McGrail DJ, Pilié PG, Rashid NU, et al." ;
  onco:sections <https://onco.cc/fronts/diagnostics/> ;
  onco:technologies <https://onco.cc/technologies/tmb-testing/> ;
  onco:terms <https://onco.cc/terms/tmb/>, <https://onco.cc/terms/tumour-agnostic/> ;
  onco:journals <https://onco.cc/journals/annals-of-oncology/> .