# OnCo record paper-nakamura-triumph-ctdna-pertuzumab-trastuzumab-her2-colorectal-nat-med-2021 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-nakamura-triumph-ctdna-pertuzumab-trastuzumab-her2-colorectal-nat-med-2021/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-nakamura-triumph-ctdna-pertuzumab-trastuzumab-her2-colorectal-nat-med-2021" ;
  schema:name "Circulating tumor DNA-guided treatment with pertuzumab plus trastuzumab for HER2-amplified metastatic colorectal cancer: a phase 2 trial (TRIUMPH)"@en ;
  schema:description "The first trial to let a blood test decide who joins: patients whose plasma showed extra HER2 responded to dual HER2 antibodies just as often as those selected on tissue, while a matched group on standard salvage therapy had no responses at all."@en ;
  schema:url <https://onco.cc/key-papers/paper-nakamura-triumph-ctdna-pertuzumab-trastuzumab-her2-colorectal-nat-med-2021/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41591-021-01553-w>, <https://pubmed.ncbi.nlm.nih.gov/34764486/> ;
  schema:sameAs <https://doi.org/10.1038/s41591-021-01553-w> ;
  schema:datePublished "2021"^^xsd:gYear ;
  schema:author "Nakamura Y, Okamoto W, Kato T, et al." ;
  onco:related <https://onco.cc/biomarkers/her2-ish-amplified/>, <https://onco.cc/biomarkers/ctdna-mrd-positive/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:technologies <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/cgp/> ;
  onco:targets <https://onco.cc/targets/her2/> ;
  onco:drugs <https://onco.cc/drugs/pertuzumab/>, <https://onco.cc/drugs/trastuzumab/> ;
  onco:pathways <https://onco.cc/pathways/rtk-activation/> ;
  onco:terms <https://onco.cc/terms/ctdna/>, <https://onco.cc/terms/cfdna/>, <https://onco.cc/terms/gene-amplification/> ;
  onco:trials <https://onco.cc/trials/circulate-japan/> ;
  onco:people <https://onco.cc/people/yoshino-takayuki/> ;
  onco:journals <https://onco.cc/journals/nature-medicine/> .