# OnCo record paper-noe-cyst-malignant-progression-genomics-nat-commun-2020 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
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<https://onco.cc/key-papers/paper-noe-cyst-malignant-progression-genomics-nat-commun-2020/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-noe-cyst-malignant-progression-genomics-nat-commun-2020" ;
  schema:name "Genomic characterization of malignant progression in neoplastic pancreatic cysts"@en ;
  schema:description "Sequencing 148 samples from cysts and the small cancers beside them established that both IPMNs and mucinous cystic neoplasms are true precursors, and that SMAD4 and TGFBR2 mutations mark the step into invasion, with about three years between high-grade dysplasia and cancer."@en ;
  schema:url <https://onco.cc/key-papers/paper-noe-cyst-malignant-progression-genomics-nat-commun-2020/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41467-020-17917-8>, <https://pubmed.ncbi.nlm.nih.gov/32796935/> ;
  schema:sameAs <https://doi.org/10.1038/s41467-020-17917-8> ;
  schema:datePublished "2020"^^xsd:gYear ;
  schema:author "Noe M, Niknafs N, Fischer CG, et al." ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/ipmn-cystic-precursors/> ;
  onco:technologies <https://onco.cc/technologies/wes-wgs/>, <https://onco.cc/technologies/pancreatic-surveillance/> ;
  onco:targets <https://onco.cc/targets/smad4/>, <https://onco.cc/targets/tgfbr2/>, <https://onco.cc/targets/rnf43/> ;
  onco:institutions <https://onco.cc/institutions/johns-hopkins/> ;
  onco:pathways <https://onco.cc/pathways/tgf-beta/>, <https://onco.cc/pathways/wnt/>, <https://onco.cc/pathways/clonal-evolution/> ;
  onco:journals <https://onco.cc/journals/nature-communications/> .