# OnCo record paper-notini-trop2-pan-cancer-multiomic-npj-precis-oncol-2026 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
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<https://onco.cc/key-papers/paper-notini-trop2-pan-cancer-multiomic-npj-precis-oncol-2026/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-notini-trop2-pan-cancer-multiomic-npj-precis-oncol-2026" ;
  schema:name "Pan-cancer multi-omic integration of Trop2 reveals biological determinants and translational implications for ADC therapy"@en ;
  schema:description "Across more than 20,000 tumour and normal samples, how much TROP2 a tissue makes was set mainly by chemical marks on its DNA rather than by mutations in its gene."@en ;
  schema:url <https://onco.cc/key-papers/paper-notini-trop2-pan-cancer-multiomic-npj-precis-oncol-2026/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41698-026-01523-w>, <https://pubmed.ncbi.nlm.nih.gov/42297906/> ;
  schema:sameAs <https://doi.org/10.1038/s41698-026-01523-w> ;
  schema:datePublished "2026"^^xsd:gYear ;
  schema:author "Notini G, Galbardi B, Viale G, et al." ;
  onco:cancers <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/tnbc/> ;
  onco:sections <https://onco.cc/fronts/adcs/> ;
  onco:technologies <https://onco.cc/technologies/methylation-profiling/> ;
  onco:targets <https://onco.cc/targets/trop2/> ;
  onco:drugs <https://onco.cc/drugs/sacituzumab-govitecan/>, <https://onco.cc/drugs/datopotamab-deruxtecan/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-subclone-attribution-residual-disease/> .