# OnCo record paper-pathfinder-lancet-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-pathfinder-lancet-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-pathfinder-lancet-2023" ;
  schema:name "PATHFINDER: the first prospective test of a multi-cancer blood test in people without symptoms"@en ;
  schema:description "In 6,621 adults over 50, the Galleri test flagged a cancer signal in 1.4%, of whom 38% turned out to have cancer; diagnostic work-up took about two months for true positives and over five months for false positives."@en ;
  schema:url <https://onco.cc/key-papers/paper-pathfinder-lancet-2023/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/S0140-6736(23)01700-2>, <https://clinicaltrials.gov/study/NCT04241796> ;
  schema:sameAs <https://doi.org/10.1016/S0140-6736(23)01700-2> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "Schrag D, Beer TM, McDonnell CH, et al." ;
  onco:related <https://onco.cc/ideas/idea-prev-mced-positive-resolution-pathway/>, <https://onco.cc/ideas/idea-prev-mced-pretest-decision-aid/> ;
  onco:sections <https://onco.cc/fronts/early-detection/> ;
  onco:technologies <https://onco.cc/technologies/mced/>, <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/methylation-profiling/> ;
  onco:drugs <https://onco.cc/drugs/galleri/> ;
  onco:institutions <https://onco.cc/institutions/dana-farber/> ;
  onco:terms <https://onco.cc/terms/ppv/>, <https://onco.cc/terms/stage-shift/> ;
  onco:trials <https://onco.cc/trials/pathfinder-2/>, <https://onco.cc/trials/nhs-galleri/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-early-detection/>, <https://onco.cc/bottlenecks/b-overdiagnosis/>, <https://onco.cc/bottlenecks/b-biomarker-validation/> ;
  onco:journals <https://onco.cc/journals/lancet/> .