# OnCo record paper-profound-nejm-2020 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-profound-nejm-2020/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-profound-nejm-2020" ;
  schema:name "PROfound: olaparib for metastatic castration-resistant prostate cancer with homologous recombination repair gene alterations"@en ;
  schema:description "In men with metastatic castration-resistant prostate cancer carrying BRCA1, BRCA2 or ATM alterations who had progressed on hormonal therapy, the PARP inhibitor olaparib delayed progression and lengthened survival compared with another hormonal agent."@en ;
  schema:url <https://onco.cc/key-papers/paper-profound-nejm-2020/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1911440>, <https://pubmed.ncbi.nlm.nih.gov/32343890/> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa1911440> ;
  schema:datePublished "2020"^^xsd:gYear ;
  schema:author "de Bono J, Mateo J, Fizazi K, et al." ;
  onco:cancers <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:drugs <https://onco.cc/drugs/olaparib/> ;
  onco:trials <https://onco.cc/trials/profound/> ;
  onco:journals <https://onco.cc/journals/nejm/> .