# OnCo record paper-quigley-structural-variation-mcrpc-cell-2018 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-quigley-structural-variation-mcrpc-cell-2018/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-quigley-structural-variation-mcrpc-cell-2018" ;
  schema:name "Genomic hallmarks and structural variation in metastatic prostate cancer"@en ;
  schema:description "Reading 101 advanced prostate cancers by whole genome rather than by gene panel found that four out of five had amplified a stretch of DNA that switches the androgen receptor on, sitting more than half a million letters away from the gene itself, where no ordinary test would look."@en ;
  schema:url <https://onco.cc/key-papers/paper-quigley-structural-variation-mcrpc-cell-2018/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.cell.2018.06.039>, <https://pubmed.ncbi.nlm.nih.gov/30033370/> ;
  schema:sameAs <https://doi.org/10.1016/j.cell.2018.06.039> ;
  schema:datePublished "2018"^^xsd:gYear ;
  schema:author "Quigley DA, Dang HX, Zhao SG, et al." ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:technologies <https://onco.cc/technologies/wes-wgs/>, <https://onco.cc/technologies/rna-seq/> ;
  onco:targets <https://onco.cc/targets/androgen-receptor/>, <https://onco.cc/targets/cdk12/>, <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/brca/> ;
  onco:pathways <https://onco.cc/pathways/ar-signaling/>, <https://onco.cc/pathways/chromosomal-instability/>, <https://onco.cc/pathways/homologous-recombination-repair/>, <https://onco.cc/pathways/mutagenesis-signatures/> ;
  onco:terms <https://onco.cc/terms/gene-amplification/>, <https://onco.cc/terms/copy-number-variation-term/>, <https://onco.cc/terms/somatic-mutations-wxs-wgs/>, <https://onco.cc/terms/castration-resistance/> ;
  onco:journals <https://onco.cc/journals/cell/> .