# OnCo record paper-ramp-201-avutometinib-defactinib-lgsoc-jco-2025 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-ramp-201-avutometinib-defactinib-lgsoc-jco-2025/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-ramp-201-avutometinib-defactinib-lgsoc-jco-2025" ;
  schema:name "RAMP 201: avutometinib with or without defactinib in recurrent low-grade serous ovarian cancer"@en ;
  schema:description "The combination of the RAF/MEK clamp avutometinib and the FAK inhibitor defactinib shrank tumours in about a third of women with recurrent low-grade serous ovarian cancer and in 44 percent of those with KRAS mutations, leading to the first approval specific to this disease."@en ;
  schema:url <https://onco.cc/key-papers/paper-ramp-201-avutometinib-defactinib-lgsoc-jco-2025/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO-25-00112>, <https://pubmed.ncbi.nlm.nih.gov/40644648/> ;
  schema:sameAs <https://doi.org/10.1200/JCO-25-00112> ;
  schema:datePublished "2025"^^xsd:gYear ;
  schema:author "Banerjee SN, Van Nieuwenhuysen E, Aghajanian C, et al." ;
  onco:cancers <https://onco.cc/cancers/low-grade-serous-ovarian-cancer/> ;
  onco:trials <https://onco.cc/trials/ramp-201/> ;
  onco:journals <https://onco.cc/journals/jco/> .