# OnCo record paper-reiss-rucaparib-maintenance-brca-palb2-pancreatic-jco-2021 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-reiss-rucaparib-maintenance-brca-palb2-pancreatic-jco-2021/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-reiss-rucaparib-maintenance-brca-palb2-pancreatic-jco-2021" ;
  schema:name "Phase II study of maintenance rucaparib in patients with platinum-sensitive advanced pancreatic cancer and a pathogenic germline or somatic variant in BRCA1, BRCA2, or PALB2"@en ;
  schema:description "Rucaparib maintenance after platinum chemotherapy kept 60% of 42 patients progression-free at six months, with responses in germline BRCA2, germline PALB2 and somatic BRCA2 carriers, widening the group PARP inhibitors may help beyond POLO's germline BRCA rule."@en ;
  schema:url <https://onco.cc/key-papers/paper-reiss-rucaparib-maintenance-brca-palb2-pancreatic-jco-2021/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.21.00003>, <https://pubmed.ncbi.nlm.nih.gov/33970687/> ;
  schema:sameAs <https://doi.org/10.1200/JCO.21.00003> ;
  schema:datePublished "2021"^^xsd:gYear ;
  schema:author "Reiss KA, Mick R, O'Hara MH, et al." ;
  onco:related <https://onco.cc/biomarkers/brca-germline/>, <https://onco.cc/biomarkers/brca-somatic/> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/brca-palb2-pdac/>, <https://onco.cc/cancers/metastatic-pdac/> ;
  onco:targets <https://onco.cc/targets/brca/>, <https://onco.cc/targets/palb2/> ;
  onco:drugs <https://onco.cc/drugs/rucaparib/> ;
  onco:institutions <https://onco.cc/institutions/penn-abramson/> ;
  onco:terms <https://onco.cc/terms/synthetic-lethality/>, <https://onco.cc/terms/germline-vs-somatic/> ;
  onco:people <https://onco.cc/people/robert-vonderheide/> ;
  onco:journals <https://onco.cc/journals/jco/> .