# OnCo record paper-relativity-047-nejm-2022 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-relativity-047-nejm-2022/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-relativity-047-nejm-2022" ;
  schema:name "RELATIVITY-047: relatlimab plus nivolumab, the first LAG-3 checkpoint combination, in untreated advanced melanoma"@en ;
  schema:description "Adding an antibody against a second immune brake, LAG-3, to nivolumab delayed progression in advanced melanoma compared with nivolumab alone, with far fewer serious side effects than the ipilimumab combination."@en ;
  schema:url <https://onco.cc/key-papers/paper-relativity-047-nejm-2022/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2109970>, <https://clinicaltrials.gov/study/NCT03470922> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa2109970> ;
  schema:datePublished "2022"^^xsd:gYear ;
  schema:author "Tawbi HA, Schadendorf D, Lipson EJ, et al." ;
  onco:cancers <https://onco.cc/cancers/melanoma/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/lag3/>, <https://onco.cc/targets/pd1/> ;
  onco:drugs <https://onco.cc/drugs/relatlimab-nivolumab/>, <https://onco.cc/drugs/nivolumab/> ;
  onco:companies <https://onco.cc/companies/bms/> ;
  onco:institutions <https://onco.cc/institutions/md-anderson/> ;
  onco:terms <https://onco.cc/terms/pfs/>, <https://onco.cc/terms/os/>, <https://onco.cc/terms/irae/>, <https://onco.cc/terms/first-line/> ;
  onco:trials <https://onco.cc/trials/checkmate-067/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-immunotherapy-response/>, <https://onco.cc/bottlenecks/b-toxicity-qol/>, <https://onco.cc/bottlenecks/b-combination-space/> ;
  onco:journals <https://onco.cc/journals/nejm/> .