# OnCo record paper-reproducibility-project-cancer-biology-elife-2021 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-reproducibility-project-cancer-biology-elife-2021/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-reproducibility-project-cancer-biology-elife-2021" ;
  schema:name "Reproducibility Project: Cancer Biology found that landmark preclinical results mostly shrank or vanished on replication"@en ;
  schema:description "An eight-year effort to repeat 50 experiments from 23 high-impact cancer biology papers found that replication effect sizes were on average 85% smaller than the originals, and fewer than half of the effects replicated by most criteria."@en ;
  schema:url <https://onco.cc/key-papers/paper-reproducibility-project-cancer-biology-elife-2021/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.7554/eLife.71601>, <https://doi.org/10.7554/eLife.67995> ;
  schema:sameAs <https://doi.org/10.7554/eLife.71601> ;
  schema:datePublished "2021"^^xsd:gYear ;
  schema:author "Errington TM, Mathur M, Soderberg CK, et al." ;
  onco:related <https://onco.cc/ideas/idea-tr1-surrogate-validation-programme/>, <https://onco.cc/ideas/idea-fund-public-nonprofit-cro/> ;
  onco:sections <https://onco.cc/fronts/drug-discovery/> ;
  onco:technologies <https://onco.cc/technologies/pdx-models/>, <https://onco.cc/technologies/organoids/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-reproducibility/>, <https://onco.cc/bottlenecks/b-translational-valley/>, <https://onco.cc/bottlenecks/b-preclinical-models/>, <https://onco.cc/bottlenecks/b-negative-results/> ;
  onco:journals <https://onco.cc/journals/elife/> .