# OnCo record paper-rhim-stroma-restrains-pancreatic-cancer-cell-2014 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-rhim-stroma-restrains-pancreatic-cancer-cell-2014/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-rhim-stroma-restrains-pancreatic-cancer-cell-2014" ;
  schema:name "Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma"@en ;
  schema:description "Removing the hedgehog signal that builds the scar tissue around pancreatic tumours in mice gave less stroma but more aggressive, more vascular cancers, and only anti-angiogenic treatment helped them."@en ;
  schema:url <https://onco.cc/key-papers/paper-rhim-stroma-restrains-pancreatic-cancer-cell-2014/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.ccr.2014.04.021>, <https://pubmed.ncbi.nlm.nih.gov/24856585/> ;
  schema:sameAs <https://doi.org/10.1016/j.ccr.2014.04.021> ;
  schema:datePublished "2014"^^xsd:gYear ;
  schema:author "Rhim AD, Oberstein PE, Thomas DH, et al." ;
  onco:cancers <https://onco.cc/cancers/pancreatic/> ;
  onco:institutions <https://onco.cc/institutions/columbia-hicc/> ;
  onco:pathways <https://onco.cc/pathways/hedgehog/>, <https://onco.cc/pathways/caf-activation-desmoplasia/>, <https://onco.cc/pathways/vegf-angiogenesis/> ;
  onco:terms <https://onco.cc/terms/desmoplasia/> ;
  onco:journals <https://onco.cc/journals/cancer-cell/> .