# OnCo record paper-ribas-wolchok-checkpoint-blockade-science-2018 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-ribas-wolchok-checkpoint-blockade-science-2018/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-ribas-wolchok-checkpoint-blockade-science-2018" ;
  schema:name "Ribas and Wolchok 2018: cancer immunotherapy using checkpoint blockade"@en ;
  schema:description "A review by two of the field's leading trialists, written as checkpoint inhibitors reached a dozen cancers, explaining how CTLA-4 and PD-1 blockade work, why only some patients respond, and how resistance arises."@en ;
  schema:url <https://onco.cc/key-papers/paper-ribas-wolchok-checkpoint-blockade-science-2018/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1126/science.aar4060> ;
  schema:sameAs <https://doi.org/10.1126/science.aar4060> ;
  schema:datePublished "2018"^^xsd:gYear ;
  schema:author "Ribas A, Wolchok JD." ;
  onco:related <https://onco.cc/key-papers/paper-pardoll-immune-checkpoint-blockade-nrc-2012/>, <https://onco.cc/key-papers/paper-tumeh-pd1-adaptive-immune-resistance-nature-2014/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/ctla4/>, <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/pdl1/> ;
  onco:institutions <https://onco.cc/institutions/ucla-jonsson/>, <https://onco.cc/institutions/mskcc/> ;
  onco:terms <https://onco.cc/terms/immune-checkpoint/>, <https://onco.cc/terms/tmb/>, <https://onco.cc/terms/irae/> ;
  onco:people <https://onco.cc/people/antoni-ribas/>, <https://onco.cc/people/jedd-wolchok/> .