# OnCo record paper-ricciuti-stk11-keap1-kras-immunotherapy-jto-2022 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-ricciuti-stk11-keap1-kras-immunotherapy-jto-2022/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-ricciuti-stk11-keap1-kras-immunotherapy-jto-2022" ;
  schema:name "Diminished efficacy of programmed death-(ligand)1 inhibition in STK11- and KEAP1-mutant lung adenocarcinoma is affected by KRAS mutation status"@en ;
  schema:description "Two genes long blamed for immunotherapy failure in lung cancer turn out to matter only when the tumour also has a mutated KRAS gene. In tumours without it, the same mutations made no difference at all."@en ;
  schema:url <https://onco.cc/key-papers/paper-ricciuti-stk11-keap1-kras-immunotherapy-jto-2022/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.jtho.2021.10.013>, <https://pubmed.ncbi.nlm.nih.gov/34740862/> ;
  schema:sameAs <https://doi.org/10.1016/j.jtho.2021.10.013> ;
  schema:datePublished "2022"^^xsd:gYear ;
  schema:author "Ricciuti B, Arbour KC, Lin JJ, et al." ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/cgp/> ;
  onco:targets <https://onco.cc/targets/stk11/>, <https://onco.cc/targets/keap1/>, <https://onco.cc/targets/kras/>, <https://onco.cc/targets/pdl1/>, <https://onco.cc/targets/pd1/> ;
  onco:institutions <https://onco.cc/institutions/dana-farber/>, <https://onco.cc/institutions/mgh/>, <https://onco.cc/institutions/mskcc/>, <https://onco.cc/institutions/md-anderson/> ;
  onco:pathways <https://onco.cc/pathways/t-cell-exhaustion/>, <https://onco.cc/pathways/keap1-nrf2/>, <https://onco.cc/pathways/pd1-checkpoint/> ;
  onco:terms <https://onco.cc/terms/stk11-keap1/>, <https://onco.cc/terms/kras-mutation-subtypes/>, <https://onco.cc/terms/cold-vs-hot/> ;
  onco:people <https://onco.cc/people/ferdinandos-skoulidis/> ;
  onco:journals <https://onco.cc/journals/journal-of-thoracic-oncology/> .