# OnCo record paper-ricciuti-tmb-pd-l1-levels-jama-oncol-2022 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-ricciuti-tmb-pd-l1-levels-jama-oncol-2022/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-ricciuti-tmb-pd-l1-levels-jama-oncol-2022" ;
  schema:name "Association of high tumor mutation burden in non-small cell lung cancers with increased immune infiltration and improved clinical outcomes of PD-L1 blockade across PD-L1 expression levels"@en ;
  schema:description "Pooling more than fifteen hundred patients showed that the more mutations a lung cancer carries the better immunotherapy works, at every level of the PD-L1 stain, but the best dividing line was about twice the number the licensing authorities use."@en ;
  schema:url <https://onco.cc/key-papers/paper-ricciuti-tmb-pd-l1-levels-jama-oncol-2022/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1001/jamaoncol.2022.1981>, <https://pubmed.ncbi.nlm.nih.gov/35708671/> ;
  schema:sameAs <https://doi.org/10.1001/jamaoncol.2022.1981> ;
  schema:datePublished "2022"^^xsd:gYear ;
  schema:author "Ricciuti B, Wang X, Alessi JV, et al." ;
  onco:related <https://onco.cc/biomarkers/tmb-high/>, <https://onco.cc/biomarkers/pd-l1-tps/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:technologies <https://onco.cc/technologies/tmb-testing/>, <https://onco.cc/technologies/cgp/>, <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/single-cell-spatial/> ;
  onco:targets <https://onco.cc/targets/pdl1/>, <https://onco.cc/targets/pd1/> ;
  onco:institutions <https://onco.cc/institutions/dana-farber/>, <https://onco.cc/institutions/mskcc/> ;
  onco:pathways <https://onco.cc/pathways/cancer-immunity-cycle/>, <https://onco.cc/pathways/pd1-checkpoint/> ;
  onco:terms <https://onco.cc/terms/tmb/>, <https://onco.cc/terms/neoantigen/>, <https://onco.cc/terms/cold-vs-hot/> ;
  onco:people <https://onco.cc/people/matthew-hellmann/> ;
  onco:journals <https://onco.cc/journals/jama-oncology/> .
