# OnCo record paper-rojas-mrna-neoantigen-vaccine-pancreatic-nature-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-rojas-mrna-neoantigen-vaccine-pancreatic-nature-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-rojas-mrna-neoantigen-vaccine-pancreatic-nature-2023" ;
  schema:name "Rojas 2023: a personalised mRNA vaccine trained T cells against each patient's pancreatic cancer, and those who responded stayed cancer-free longer"@en ;
  schema:description "Individualised mRNA vaccines encoding up to 20 of each patient's tumour mutations generated strong T-cell responses in half of pancreatic cancer patients after surgery, and those responders had far fewer relapses."@en ;
  schema:url <https://onco.cc/key-papers/paper-rojas-mrna-neoantigen-vaccine-pancreatic-nature-2023/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://pubmed.ncbi.nlm.nih.gov/?term=Personalized%20RNA%20neoantigen%20vaccines%20stimulate%20T%20cells%20in%20pancreatic%20cancer%20Rojas%20Nature%202023>, <https://clinicaltrials.gov/study/NCT04161755> ;
  schema:sameAs <https://doi.org/10.1038/s41586-023-06063-y> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "Rojas LA, Sethna Z, Soares KC, et al." ;
  onco:related <https://onco.cc/pairings/vaccine-plus-pd1/>, <https://onco.cc/key-papers/paper-sethna-rna-neoantigen-vaccine-long-lived-t-cells-nature-2025/> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/melanoma/> ;
  onco:technologies <https://onco.cc/technologies/neoantigen-mrna-vaccine/> ;
  onco:targets <https://onco.cc/targets/pd1/> ;
  onco:drugs <https://onco.cc/drugs/autogene-cevumeran/>, <https://onco.cc/drugs/atezolizumab/>, <https://onco.cc/drugs/intismeran-autogene/> ;
  onco:companies <https://onco.cc/companies/biontech/>, <https://onco.cc/companies/roche-genentech/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/> ;
  onco:terms <https://onco.cc/terms/neoantigen/>, <https://onco.cc/terms/tmb/> ;
  onco:trials <https://onco.cc/trials/interpath-001/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-immunotherapy-response/>, <https://onco.cc/bottlenecks/b-manufacturing-cell-therapy/>, <https://onco.cc/bottlenecks/b-tme-immunosuppression/> ;
  onco:journals <https://onco.cc/journals/nature/> .