# OnCo record paper-roman-anderson-eclinicalmedicine-2025 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-roman-anderson-eclinicalmedicine-2025/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-roman-anderson-eclinicalmedicine-2025" ;
  schema:name "Avasopasem manganese treatment for severe oral mucositis from chemoradiotherapy for locally advanced head and neck cancer: phase 3 randomized controlled trial (ROMAN)"@en ;
  schema:description "Giving avasopasem before each radiotherapy session lowered the share of head and neck cancer patients who got severe mouth ulcers from 64 to 54 percent and cut how long the ulcers lasted from 18 days to 8, but the gain was smaller than hoped and the FDA wanted another trial."@en ;
  schema:url <https://onco.cc/key-papers/paper-roman-anderson-eclinicalmedicine-2025/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.eclinm.2025.103539>, <https://pubmed.ncbi.nlm.nih.gov/41127563/>, <https://clinicaltrials.gov/study/NCT03689712> ;
  schema:sameAs <https://doi.org/10.1016/j.eclinm.2025.103539> ;
  schema:datePublished "2025"^^xsd:gYear ;
  schema:author "Anderson C, Lee CM, Kelley JR, et al." ;
  onco:cancers <https://onco.cc/cancers/head-and-neck/> ;
  onco:technologies <https://onco.cc/technologies/radioprotectors/> ;
  onco:drugs <https://onco.cc/drugs/avasopasem-manganese/> ;
  onco:companies <https://onco.cc/companies/galera-therapeutics/> ;
  onco:trials <https://onco.cc/trials/roman/> .