# OnCo record paper-sato-lgr5-organoids-nature-2009 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
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<https://onco.cc/key-papers/paper-sato-lgr5-organoids-nature-2009/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-sato-lgr5-organoids-nature-2009" ;
  schema:name "Sato 2009: single Lgr5 stem cells build crypt-villus organoids"@en ;
  schema:description "The experiment that invented organoids: a single intestinal stem cell, given three growth factors in a gel, grew into a miniature gut lining that could be kept alive indefinitely, a method since extended to tumours from individual patients."@en ;
  schema:url <https://onco.cc/key-papers/paper-sato-lgr5-organoids-nature-2009/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/nature07935> ;
  schema:sameAs <https://doi.org/10.1038/nature07935> ;
  schema:datePublished "2009"^^xsd:gYear ;
  schema:author "Sato T, Vries RG, Snippert HJ, et al." ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:technologies <https://onco.cc/technologies/organoids/>, <https://onco.cc/technologies/organoid-guided-therapy-scale/> ;
  onco:institutions <https://onco.cc/institutions/umc-utrecht/> ;
  onco:terms <https://onco.cc/terms/stem-cell/> .