# OnCo record paper-scagliotti-cisplatin-pemetrexed-histology-jco-2008 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-scagliotti-cisplatin-pemetrexed-histology-jco-2008/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-scagliotti-cisplatin-pemetrexed-histology-jco-2008" ;
  schema:name "Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer"@en ;
  schema:description "1,725 patients, two chemotherapy combinations, identical survival overall. But split by what the tumour looked like down a microscope, one drug was better for adenocarcinoma and the other for squamous cancer. Histology started choosing the drug."@en ;
  schema:url <https://onco.cc/key-papers/paper-scagliotti-cisplatin-pemetrexed-histology-jco-2008/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.2007.15.0375>, <https://pubmed.ncbi.nlm.nih.gov/18506025/>, <https://europepmc.org/article/MED/37146426> ;
  onco:tag "lung-evidence" ;
  schema:sameAs <https://doi.org/10.1200/JCO.2007.15.0375> ;
  schema:datePublished "2008"^^xsd:gYear ;
  schema:author "Scagliotti GV, Parikh P, von Pawel J, et al." ;
  onco:related <https://onco.cc/roadmaps/chemotherapy-roadmap/>, <https://onco.cc/key-papers/paper-schiller-ecog-1594-four-chemotherapy-regimens-nejm-2002/>, <https://onco.cc/key-papers/paper-keynote-189-nejm-2018/> ;
  onco:cancers <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/lung-adenocarcinoma/>, <https://onco.cc/cancers/lung-squamous-cell-carcinoma/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/> ;
  onco:drugs <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/pemetrexed/>, <https://onco.cc/drugs/gemcitabine/> ;
  onco:terms <https://onco.cc/terms/histology/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-biomarker-validation/>, <https://onco.cc/bottlenecks/b-dose-optimisation/> ;
  onco:journals <https://onco.cc/journals/jco/> .