# OnCo record paper-sethna-rna-neoantigen-vaccine-long-lived-t-cells-nature-2025 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-sethna-rna-neoantigen-vaccine-long-lived-t-cells-nature-2025/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-sethna-rna-neoantigen-vaccine-long-lived-t-cells-nature-2025" ;
  schema:name "RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer"@en ;
  schema:description "The 2025 follow-up of the personalised mRNA vaccine trial in pancreatic cancer: at three years, patients whose immune systems responded to the vaccine had still mostly not relapsed, and the T cells the vaccine made were predicted to live for years."@en ;
  schema:url <https://onco.cc/key-papers/paper-sethna-rna-neoantigen-vaccine-long-lived-t-cells-nature-2025/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41586-024-08508-4>, <https://pubmed.ncbi.nlm.nih.gov/39972124/>, <https://clinicaltrials.gov/study/NCT04161755>, <https://clinicaltrials.gov/study/NCT05968326> ;
  onco:tag "pancreatic-evidence" ;
  schema:sameAs <https://doi.org/10.1038/s41586-024-08508-4> ;
  schema:datePublished "2025"^^xsd:gYear ;
  schema:author "Sethna Z, Guasp P, Reiche C, et al." ;
  onco:related <https://onco.cc/key-papers/paper-rojas-mrna-neoantigen-vaccine-pancreatic-nature-2023/>, <https://onco.cc/roadmaps/immunotherapy-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/resectable-pdac/> ;
  onco:technologies <https://onco.cc/technologies/neoantigen-mrna-vaccine/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:drugs <https://onco.cc/drugs/autogene-cevumeran/>, <https://onco.cc/drugs/atezolizumab/>, <https://onco.cc/drugs/folfirinox/> ;
  onco:companies <https://onco.cc/companies/biontech/>, <https://onco.cc/companies/roche-genentech/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/> ;
  onco:terms <https://onco.cc/terms/neoantigen/>, <https://onco.cc/terms/cold-vs-hot/> ;
  onco:trials <https://onco.cc/trials/nct05968326/> ;
  onco:people <https://onco.cc/people/vinod-balachandran/>, <https://onco.cc/people/ugur-sahin/>, <https://onco.cc/people/eileen-oreilly/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-tme-immunosuppression/>, <https://onco.cc/bottlenecks/b-immunotherapy-response/> ;
  onco:journals <https://onco.cc/journals/nature/> .