# OnCo record paper-singhi-targeted-genome-profiling-3594-pdac-gastroenterology-2019 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-singhi-targeted-genome-profiling-3594-pdac-gastroenterology-2019/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-singhi-targeted-genome-profiling-3594-pdac-gastroenterology-2019" ;
  schema:name "Real-time targeted genome profile analysis of pancreatic ductal adenocarcinomas identifies genetic alterations that might be targeted with existing drugs or used as biomarkers"@en ;
  schema:description "Targeted sequencing of 3,594 pancreatic cancers, the largest such series, found KRAS in 88%, a drug-matchable alteration in 17%, BRCA or FANC repair gene changes in 14%, and microsatellite instability or very high mutation burden in only 0.5%."@en ;
  schema:url <https://onco.cc/key-papers/paper-singhi-targeted-genome-profiling-3594-pdac-gastroenterology-2019/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1053/j.gastro.2019.02.037>, <https://pubmed.ncbi.nlm.nih.gov/30836094/> ;
  schema:sameAs <https://doi.org/10.1053/j.gastro.2019.02.037> ;
  schema:datePublished "2019"^^xsd:gYear ;
  schema:author "Singhi AD, George B, Greenbowe JR, et al." ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/kras-wild-type-pdac/>, <https://onco.cc/cancers/msi-high-pdac/> ;
  onco:technologies <https://onco.cc/technologies/tmb-testing/>, <https://onco.cc/technologies/msi-mmr-testing/> ;
  onco:targets <https://onco.cc/targets/kras/>, <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/cdkn2a/>, <https://onco.cc/targets/smad4/>, <https://onco.cc/targets/brca/> ;
  onco:drugs <https://onco.cc/drugs/foundationone-cdx/> ;
  onco:institutions <https://onco.cc/institutions/upmc-hillman/> ;
  onco:terms <https://onco.cc/terms/tmb/>, <https://onco.cc/terms/msi/>, <https://onco.cc/terms/ngs/> ;
  onco:people <https://onco.cc/people/anirban-maitra/>, <https://onco.cc/people/talia-golan/> ;
  onco:journals <https://onco.cc/journals/gastroenterology/> .
