# OnCo record paper-slamon-trastuzumab-nejm-2001 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-slamon-trastuzumab-nejm-2001/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-slamon-trastuzumab-nejm-2001" ;
  schema:name "Slamon 2001: adding trastuzumab to chemotherapy for HER2-positive metastatic breast cancer"@en ;
  schema:description "The trial that made trastuzumab standard: adding the HER2 antibody to chemotherapy slowed progression and prolonged life in women whose breast cancers overexpressed HER2, at the cost of heart weakening when it was paired with anthracyclines."@en ;
  schema:url <https://onco.cc/key-papers/paper-slamon-trastuzumab-nejm-2001/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJM200103153441101> ;
  schema:sameAs <https://doi.org/10.1056/NEJM200103153441101> ;
  schema:datePublished "2001"^^xsd:gYear ;
  schema:author "Slamon DJ, Leyland-Jones B, Shak S, et al." ;
  onco:related <https://onco.cc/key-papers/paper-slamon-her2-amplification-science-1987/> ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/> ;
  onco:targets <https://onco.cc/targets/her2/> ;
  onco:drugs <https://onco.cc/drugs/trastuzumab/>, <https://onco.cc/drugs/paclitaxel/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:terms <https://onco.cc/terms/os/>, <https://onco.cc/terms/orr/> ;
  onco:people <https://onco.cc/people/dennis-slamon/> .