# OnCo record paper-smile-chemotherapy-nk-t-cell-lymphoma-jco-2011 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-smile-chemotherapy-nk-t-cell-lymphoma-jco-2011/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-smile-chemotherapy-nk-t-cell-lymphoma-jco-2011" ;
  schema:name "Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study"@en ;
  schema:alternateName "SMILE"@en, "Yamaguchi 2011"@en ;
  schema:description "An asparaginase-based regimen produced a response in four out of five people with an aggressive nasal lymphoma that resists ordinary chemotherapy, and nearly all of them developed dangerously low white cell counts."@en ;
  schema:url <https://onco.cc/key-papers/paper-smile-chemotherapy-nk-t-cell-lymphoma-jco-2011/> ;
  schema:dateModified "2026-10-01"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.2011.35.6287>, <https://pubmed.ncbi.nlm.nih.gov/21990393/>, <https://europepmc.org/article/MED/21990393>, <https://doi.org/10.1002/ajh.21256>, <https://doi.org/10.1080/10428190410001693524> ;
  onco:tag "lymphoma-evidence" ;
  schema:sameAs <https://doi.org/10.1200/JCO.2011.35.6287> ;
  schema:datePublished "2011"^^xsd:gYear ;
  schema:author "Yamaguchi M, Kwong YL, Kim WS, et al." ;
  onco:related <https://onco.cc/roadmaps/lymphoma-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/peripheral-t-cell-lymphoma/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:sections <https://onco.cc/fronts/chemotherapy/> ;
  onco:drugs <https://onco.cc/drugs/dexamethasone/>, <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/ifosfamide/>, <https://onco.cc/drugs/asparaginase/>, <https://onco.cc/drugs/etoposide/> ;
  onco:terms <https://onco.cc/terms/orr/>, <https://onco.cc/terms/complete-response/>, <https://onco.cc/terms/autologous-transplant/> ;
  onco:trials <https://onco.cc/trials/smile-enktl/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-rare-cancers/>, <https://onco.cc/bottlenecks/b-global-access/> ;
  onco:journals <https://onco.cc/journals/jco/> .