# OnCo record paper-solar-1-alpelisib-nejm-2019 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-solar-1-alpelisib-nejm-2019/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-solar-1-alpelisib-nejm-2019" ;
  schema:name "SOLAR-1: alpelisib plus fulvestrant for PIK3CA-mutated hormone receptor-positive advanced breast cancer"@en ;
  schema:description "Alpelisib, a pill blocking the mutated PI3K-alpha enzyme, nearly doubled the time to progression when added to fulvestrant in advanced breast cancer carrying a PIK3CA mutation, at the cost of high blood sugar and rash."@en ;
  schema:url <https://onco.cc/key-papers/paper-solar-1-alpelisib-nejm-2019/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1813904>, <https://pubmed.ncbi.nlm.nih.gov/31091374/> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa1813904> ;
  schema:datePublished "2019"^^xsd:gYear ;
  schema:author "André F, Ciruelos E, Rubovszky G, et al." ;
  onco:cancers <https://onco.cc/cancers/hr-positive-metastatic-post-cdk46/> ;
  onco:drugs <https://onco.cc/drugs/alpelisib/> ;
  onco:trials <https://onco.cc/trials/solar-1/> ;
  onco:journals <https://onco.cc/journals/nejm/> .