# OnCo record paper-spotlight-lancet-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-spotlight-lancet-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-spotlight-lancet-2023" ;
  schema:name "SPOTLIGHT: zolbetuximab, the first Claudin 18.2 antibody, added to chemotherapy in gastric cancer"@en ;
  schema:description "In stomach cancers that express the protein Claudin 18.2, adding the antibody zolbetuximab to chemotherapy extended survival by nearly three months, making Claudin 18.2 a new biomarker to test for."@en ;
  schema:url <https://onco.cc/key-papers/paper-spotlight-lancet-2023/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://pubmed.ncbi.nlm.nih.gov/?term=SPOTLIGHT+zolbetuximab+mFOLFOX6+Shitara+Lancet>, <https://clinicaltrials.gov/study/NCT03504397> ;
  schema:sameAs <https://doi.org/10.1016/S0140-6736(23)00620-7> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "Shitara K, Lordick F, Bang YJ, et al." ;
  onco:cancers <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/esophageal/> ;
  onco:technologies <https://onco.cc/technologies/monoclonal-antibody/>, <https://onco.cc/technologies/histopathology-ihc/>, <https://onco.cc/technologies/companion-diagnostic/> ;
  onco:targets <https://onco.cc/targets/cldn18-2/> ;
  onco:companies <https://onco.cc/companies/astellas/> ;
  onco:institutions <https://onco.cc/institutions/ncc-japan/> ;
  onco:terms <https://onco.cc/terms/ihc/>, <https://onco.cc/terms/pfs/>, <https://onco.cc/terms/os/>, <https://onco.cc/terms/adcc/>, <https://onco.cc/terms/first-line/> ;
  onco:people <https://onco.cc/people/shitara-kohei/>, <https://onco.cc/people/bang-yung-jue/>, <https://onco.cc/people/xu-rui-hua/>, <https://onco.cc/people/kang-yoon-koo/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-biomarker-validation/>, <https://onco.cc/bottlenecks/b-combination-space/> ;
  onco:journals <https://onco.cc/journals/lancet/> .