# OnCo record paper-staaf-tnbc-whole-genome-scan-b-nat-med-2019 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-staaf-tnbc-whole-genome-scan-b-nat-med-2019/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-staaf-tnbc-whole-genome-scan-b-nat-med-2019" ;
  schema:name "Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study"@en ;
  schema:description "Reading the whole genome of 254 Swedish triple-negative cancers showed that 59% carry the signature of broken BRCA-type DNA repair, two-thirds of them explained by BRCA1 or BRCA2 mutation, BRCA1 or RAD51C promoter methylation or PALB2 loss, and that these patients did best on standard chemotherapy."@en ;
  schema:url <https://onco.cc/key-papers/paper-staaf-tnbc-whole-genome-scan-b-nat-med-2019/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41591-019-0582-4>, <https://pubmed.ncbi.nlm.nih.gov/31570822/> ;
  schema:sameAs <https://doi.org/10.1038/s41591-019-0582-4> ;
  schema:datePublished "2019"^^xsd:gYear ;
  schema:author "Staaf J, Glodzik D, Bosch A, et al." ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/tnbc-early/> ;
  onco:technologies <https://onco.cc/technologies/wes-wgs/>, <https://onco.cc/technologies/hrd-testing/> ;
  onco:targets <https://onco.cc/targets/brca/>, <https://onco.cc/targets/palb2/>, <https://onco.cc/targets/rad51c/>, <https://onco.cc/targets/mmr/> ;
  onco:institutions <https://onco.cc/institutions/lund-skane/> ;
  onco:pathways <https://onco.cc/pathways/homologous-recombination-repair/>, <https://onco.cc/pathways/mutagenesis-signatures/> ;
  onco:terms <https://onco.cc/terms/hrd/>, <https://onco.cc/terms/mutational-signature/> ;
  onco:journals <https://onco.cc/journals/nature-medicine/> .