# OnCo record paper-stopsack-mcspc-genomic-alterations-outcomes-ccr-2020 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-stopsack-mcspc-genomic-alterations-outcomes-ccr-2020/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-stopsack-mcspc-genomic-alterations-outcomes-ccr-2020" ;
  schema:name "Oncogenic genomic alterations, clinical phenotypes and outcomes in metastatic castration-sensitive prostate cancer"@en ;
  schema:description "Sequencing 424 men at the point their cancer had spread but before hormone treatment failed showed which genetic changes make castration resistance come sooner, and which make it come later."@en ;
  schema:url <https://onco.cc/key-papers/paper-stopsack-mcspc-genomic-alterations-outcomes-ccr-2020/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1158/1078-0432.CCR-20-0168>, <https://pubmed.ncbi.nlm.nih.gov/32220891/>, <https://www.cbioportal.org/study/summary?id=prad_mcspc_mskcc_2020> ;
  schema:sameAs <https://doi.org/10.1158/1078-0432.CCR-20-0168> ;
  schema:datePublished "2020"^^xsd:gYear ;
  schema:author "Stopsack KH, Nandakumar S, Wibmer AG, et al." ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mhspc/> ;
  onco:technologies <https://onco.cc/technologies/cgp/> ;
  onco:targets <https://onco.cc/targets/androgen-receptor/>, <https://onco.cc/targets/spop/>, <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/cdk12/>, <https://onco.cc/targets/apc/> ;
  onco:pathways <https://onco.cc/pathways/ar-signaling/>, <https://onco.cc/pathways/p53-cell-cycle/>, <https://onco.cc/pathways/wnt/>, <https://onco.cc/pathways/myc/>, <https://onco.cc/pathways/cell-cycle-engine-cdks/> ;
  onco:terms <https://onco.cc/terms/castration-resistance/>, <https://onco.cc/terms/mcrpc-mhspc/>, <https://onco.cc/terms/driver-mutation/> ;
  onco:journals <https://onco.cc/journals/clinical-cancer-research/> .
