# OnCo record paper-strickler-mountaineer-tucatinib-trastuzumab-lancet-oncol-2023 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-strickler-mountaineer-tucatinib-trastuzumab-lancet-oncol-2023/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-strickler-mountaineer-tucatinib-trastuzumab-lancet-oncol-2023" ;
  schema:name "Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER)"@en ;
  schema:description "A HER2 pill with an antibody gave a 38 percent response rate in chemotherapy-refractory HER2-positive bowel cancer, and became the first HER2-directed regimen approved for the disease."@en ;
  schema:url <https://onco.cc/key-papers/paper-strickler-mountaineer-tucatinib-trastuzumab-lancet-oncol-2023/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/S1470-2045(23)00150-X>, <https://pubmed.ncbi.nlm.nih.gov/37142372/> ;
  onco:tag "colorectal-evidence" ;
  schema:sameAs <https://doi.org/10.1016/S1470-2045(23)00150-X> ;
  schema:datePublished "2023"^^xsd:gYear ;
  schema:author "Strickler JH, Cercek A, Siena S, et al." ;
  onco:related <https://onco.cc/key-papers/paper-sartore-bianchi-heracles-trastuzumab-lapatinib-lancet-oncol-2016/>, <https://onco.cc/key-papers/paper-siena-destiny-crc01-trastuzumab-deruxtecan-lancet-oncol-2021/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/her2-amplified-colorectal/> ;
  onco:sections <https://onco.cc/fronts/targeted-therapy/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/>, <https://onco.cc/technologies/monoclonal-antibody/> ;
  onco:targets <https://onco.cc/targets/her2/> ;
  onco:drugs <https://onco.cc/drugs/tucatinib/>, <https://onco.cc/drugs/trastuzumab/> ;
  onco:companies <https://onco.cc/companies/pfizer/>, <https://onco.cc/companies/merck/> ;
  onco:trials <https://onco.cc/trials/mountaineer/> ;
  onco:people <https://onco.cc/people/john-strickler/>, <https://onco.cc/people/andrea-cercek/>, <https://onco.cc/people/salvatore-siena/>, <https://onco.cc/people/thierry-andre/>, <https://onco.cc/people/eric-van-cutsem/>, <https://onco.cc/people/tanios-bekaii-saab/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-rare-cancers/> ;
  onco:journals <https://onco.cc/journals/lancet-oncology/> .