# OnCo record paper-struewing-brca-founder-mutations-ashkenazi-nejm-1997 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-struewing-brca-founder-mutations-ashkenazi-nejm-1997/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-struewing-brca-founder-mutations-ashkenazi-nejm-1997" ;
  schema:name "The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews"@en ;
  schema:description "The 1997 study of 5,318 Ashkenazi Jewish volunteers that measured the real-world breast cancer risk of the three founder mutations carried by more than 2 percent of that population: 56 percent by age 70, lower than the 85 percent estimated from high-risk families."@en ;
  schema:url <https://onco.cc/key-papers/paper-struewing-brca-founder-mutations-ashkenazi-nejm-1997/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJM199705153362001>, <https://pubmed.ncbi.nlm.nih.gov/9145676/> ;
  onco:tag "tnbc-evidence" ;
  schema:sameAs <https://doi.org/10.1056/NEJM199705153362001> ;
  schema:datePublished "1997"^^xsd:gYear ;
  schema:author "Struewing JP, Hartge P, Wacholder S, et al." ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/breast-cancer/> ;
  onco:targets <https://onco.cc/targets/brca/> ;
  onco:institutions <https://onco.cc/institutions/nci/> ;
  onco:terms <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/terms/gbrca-mutation/> ;
  onco:people <https://onco.cc/people/mary-claire-king/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-hereditary-risk/> ;
  onco:journals <https://onco.cc/journals/nejm/> .