# OnCo record paper-stupp-temozolomide-nejm-2005 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-stupp-temozolomide-nejm-2005/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-stupp-temozolomide-nejm-2005" ;
  schema:name "Stupp 2005: temozolomide added to radiotherapy for newly diagnosed glioblastoma"@en ;
  schema:description "Adding the oral chemotherapy temozolomide during and after radiotherapy extended median survival in glioblastoma by about two and a half months and more than doubled the number of patients alive at two years; twenty years later it is still the standard."@en ;
  schema:url <https://onco.cc/key-papers/paper-stupp-temozolomide-nejm-2005/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa043330>, <https://doi.org/10.1056/NEJMoa043331> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa043330> ;
  schema:datePublished "2005"^^xsd:gYear ;
  schema:author "Stupp R, Mason WP, van den Bent MJ, et al." ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/methylation-profiling/>, <https://onco.cc/technologies/ttfields/> ;
  onco:companies <https://onco.cc/companies/curie-nki-eortc/> ;
  onco:terms <https://onco.cc/terms/os/>, <https://onco.cc/terms/standard-of-care/> ;
  onco:people <https://onco.cc/people/roger-stupp/>, <https://onco.cc/people/michael-weller/>, <https://onco.cc/people/denis-lacombe/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-brain-delivery/>, <https://onco.cc/bottlenecks/b-negative-results/>, <https://onco.cc/bottlenecks/b-undruggable-targets/> ;
  onco:journals <https://onco.cc/journals/nejm/> .