# OnCo record paper-taplin-ar-mutation-androgen-independent-prostate-nejm-1995 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-taplin-ar-mutation-androgen-independent-prostate-nejm-1995/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-taplin-ar-mutation-androgen-independent-prostate-nejm-1995" ;
  schema:name "Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer"@en ;
  schema:description "In half of ten men whose prostate cancer had stopped responding to hormone treatment, the receptor had changed shape so that other hormones, including oestrogen, could switch it on."@en ;
  schema:url <https://onco.cc/key-papers/paper-taplin-ar-mutation-androgen-independent-prostate-nejm-1995/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJM199505253322101>, <https://pubmed.ncbi.nlm.nih.gov/7723794/> ;
  schema:sameAs <https://doi.org/10.1056/NEJM199505253322101> ;
  schema:datePublished "1995"^^xsd:gYear ;
  schema:author "Taplin ME, Bubley GJ, Shuster TD, et al." ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:technologies <https://onco.cc/technologies/cgp/> ;
  onco:targets <https://onco.cc/targets/androgen-receptor/> ;
  onco:pathways <https://onco.cc/pathways/ar-signaling/>, <https://onco.cc/pathways/resistance-routes-map/> ;
  onco:terms <https://onco.cc/terms/castration-resistance/>, <https://onco.cc/terms/resistance/>, <https://onco.cc/terms/driver-mutation/> ;
  onco:journals <https://onco.cc/journals/nejm/> .