# OnCo record paper-taylor-integrative-genomic-profiling-cancer-cell-2010 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-taylor-integrative-genomic-profiling-cancer-cell-2010/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-taylor-integrative-genomic-profiling-cancer-cell-2010" ;
  schema:name "Integrative genomic profiling of human prostate cancer"@en ;
  schema:alternateName "Taylor 2010"@en, "MSKCC prostate genomics 218 tumours"@en ;
  schema:description "The first large look at prostate cancer across copy number, gene expression and sequence at once. Its most useful finding for patients was that the pattern of gained and lost chromosome segments separates low-risk from high-risk disease better than the Gleason score does."@en ;
  schema:url <https://onco.cc/key-papers/paper-taylor-integrative-genomic-profiling-cancer-cell-2010/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.ccr.2010.05.026>, <https://pubmed.ncbi.nlm.nih.gov/20579941/> ;
  onco:tag "prostate-evidence" ;
  schema:sameAs <https://doi.org/10.1016/j.ccr.2010.05.026> ;
  schema:datePublished "2010"^^xsd:gYear ;
  schema:author "Taylor BS, Schultz N, Hieronymus H, et al." ;
  onco:related <https://onco.cc/key-papers/paper-tomlins-tmprss2-ets-fusion-science-2005/>, <https://onco.cc/key-papers/paper-grasso-mutational-landscape-lethal-crpc-nature-2012/>, <https://onco.cc/key-papers/paper-esteva-npj-digit-med/>, <https://onco.cc/roadmaps/prostate-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-high-risk/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/>, <https://onco.cc/fronts/ai-computation/> ;
  onco:technologies <https://onco.cc/technologies/cgp/> ;
  onco:targets <https://onco.cc/targets/erg/>, <https://onco.cc/targets/tmprss2/>, <https://onco.cc/targets/androgen-receptor/>, <https://onco.cc/targets/ncoa2/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/> ;
  onco:pathways <https://onco.cc/pathways/ar-signaling/>, <https://onco.cc/pathways/chromosomal-instability/>, <https://onco.cc/pathways/prostate-cancer-signalling/> ;
  onco:terms <https://onco.cc/terms/gleason-grade-group/>, <https://onco.cc/terms/ngs/>, <https://onco.cc/terms/copy-number-variation-term/>, <https://onco.cc/terms/gene-fusion/> ;
  onco:people <https://onco.cc/people/charles-sawyers/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-biomarker-validation/>, <https://onco.cc/bottlenecks/b-data-silos/>, <https://onco.cc/bottlenecks/b-tumor-heterogeneity/> ;
  onco:journals <https://onco.cc/journals/cancer-cell/> .