# OnCo record paper-tcga-breast-molecular-portraits-nature-2012 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-tcga-breast-molecular-portraits-nature-2012/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-tcga-breast-molecular-portraits-nature-2012" ;
  schema:name "Comprehensive molecular portraits of human breast tumours"@en ;
  schema:description "The Cancer Genome Atlas profiled hundreds of breast cancers on six platforms and found four main classes; the basal-like class, which is 80% triple-negative, carries TP53 mutation in 80%, frequent PTEN and RB1 loss, MYC and EGFR gains and looks molecularly like high-grade serous ovarian cancer."@en ;
  schema:url <https://onco.cc/key-papers/paper-tcga-breast-molecular-portraits-nature-2012/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/nature11412>, <https://pubmed.ncbi.nlm.nih.gov/23000897/>, <https://www.cbioportal.org/study/summary?id=brca_tcga_pub>, <https://www.cbioportal.org/study/summary?id=brca_tcga_pan_can_atlas_2018> ;
  schema:sameAs <https://doi.org/10.1038/nature11412> ;
  schema:datePublished "2012"^^xsd:gYear ;
  schema:author "Cancer Genome Atlas Network." ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/high-grade-serous-ovarian-cancer/> ;
  onco:targets <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/pik3ca/>, <https://onco.cc/targets/pten/>, <https://onco.cc/targets/rb1/>, <https://onco.cc/targets/egfr/> ;
  onco:pathways <https://onco.cc/pathways/p53-cell-cycle/>, <https://onco.cc/pathways/pi3k-akt-mtor/>, <https://onco.cc/pathways/myc/> ;
  onco:terms <https://onco.cc/terms/pam50/> ;
  onco:people <https://onco.cc/people/charles-perou/> ;
  onco:journals <https://onco.cc/journals/nature/> .