# OnCo record paper-tcga-colorectal-comprehensive-characterization-nature-2012 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-tcga-colorectal-comprehensive-characterization-nature-2012/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-tcga-colorectal-comprehensive-characterization-nature-2012" ;
  schema:name "Comprehensive molecular characterization of human colon and rectal cancer"@en ;
  schema:description "The Cancer Genome Atlas read the DNA, copy number, methylation and gene activity of 276 bowel cancers, found that one in six carries an enormous number of mutations, and showed that once those are set aside colon and rectal cancers look the same."@en ;
  schema:url <https://onco.cc/key-papers/paper-tcga-colorectal-comprehensive-characterization-nature-2012/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/nature11252>, <https://pubmed.ncbi.nlm.nih.gov/22810696/>, <https://www.cbioportal.org/study/summary?id=coadread_tcga_pub>, <https://www.cbioportal.org/study/summary?id=coadread_tcga_pan_can_atlas_2018> ;
  schema:sameAs <https://doi.org/10.1038/nature11252> ;
  schema:datePublished "2012"^^xsd:gYear ;
  schema:author "Cancer Genome Atlas Network." ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:technologies <https://onco.cc/technologies/wes-wgs/>, <https://onco.cc/technologies/rna-seq/>, <https://onco.cc/technologies/methylation-profiling/> ;
  onco:targets <https://onco.cc/targets/apc/>, <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/kras/>, <https://onco.cc/targets/smad4/>, <https://onco.cc/targets/pik3ca/>, <https://onco.cc/targets/arid1a/>, <https://onco.cc/targets/sox9/>, <https://onco.cc/targets/amer1/>, <https://onco.cc/targets/her2/>, <https://onco.cc/targets/myc-gene/> ;
  onco:institutions <https://onco.cc/institutions/nci/>, <https://onco.cc/institutions/broad-institute/> ;
  onco:pathways <https://onco.cc/pathways/colorectal-cancer-signalling/>, <https://onco.cc/pathways/wnt/>, <https://onco.cc/pathways/chromosomal-instability/>, <https://onco.cc/pathways/mismatch-repair-msi/>, <https://onco.cc/pathways/myc/> ;
  onco:terms <https://onco.cc/terms/msi/>, <https://onco.cc/terms/somatic-mutations-wxs-wgs/> ;
  onco:journals <https://onco.cc/journals/nature/> .