# OnCo record paper-tuxedo-1-trastuzumab-deruxtecan-brain-metastases-nat-med-2022 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-tuxedo-1-trastuzumab-deruxtecan-brain-metastases-nat-med-2022/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-tuxedo-1-trastuzumab-deruxtecan-brain-metastases-nat-med-2022" ;
  schema:name "TUXEDO-1: trastuzumab deruxtecan in HER2-positive breast cancer with active brain metastases"@en ;
  schema:description "In a small trial, the antibody-drug conjugate trastuzumab deruxtecan shrank brain metastases in almost three quarters of women with HER2-positive breast cancer, showing that a large antibody-based drug can work inside the brain."@en ;
  schema:url <https://onco.cc/key-papers/paper-tuxedo-1-trastuzumab-deruxtecan-brain-metastases-nat-med-2022/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41591-022-01935-8>, <https://pubmed.ncbi.nlm.nih.gov/35941372/> ;
  schema:sameAs <https://doi.org/10.1038/s41591-022-01935-8> ;
  schema:datePublished "2022"^^xsd:gYear ;
  schema:author "Bartsch R, Berghoff AS, Furtner J, et al." ;
  onco:cancers <https://onco.cc/cancers/her2-positive-breast-brain-metastases/> ;
  onco:drugs <https://onco.cc/drugs/trastuzumab/>, <https://onco.cc/drugs/trastuzumab-deruxtecan/> ;
  onco:trials <https://onco.cc/trials/tuxedo-1/> ;
  onco:journals <https://onco.cc/journals/nature-medicine/> .