# OnCo record paper-verwaal-cytoreduction-hipec-peritoneal-colorectal-jco-2003 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-verwaal-cytoreduction-hipec-peritoneal-colorectal-jco-2003/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-verwaal-cytoreduction-hipec-peritoneal-colorectal-jco-2003" ;
  schema:name "Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer"@en ;
  schema:description "The Dutch trial that put heated chemotherapy into the abdomen after stripping out all visible tumour, and nearly doubled median survival from 12.6 to 22.3 months. Eight percent of patients died of the treatment."@en ;
  schema:url <https://onco.cc/key-papers/paper-verwaal-cytoreduction-hipec-peritoneal-colorectal-jco-2003/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.2003.04.187>, <https://pubmed.ncbi.nlm.nih.gov/14551293/> ;
  onco:tag "colorectal-evidence" ;
  schema:sameAs <https://doi.org/10.1200/JCO.2003.04.187> ;
  schema:datePublished "2003"^^xsd:gYear ;
  schema:author "Verwaal VJ, van Ruth S, de Bree E, et al." ;
  onco:related <https://onco.cc/key-papers/paper-quenet-prodige-7-hipec-peritoneal-colorectal-lancet-oncol-2021/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:sections <https://onco.cc/fronts/surgery/> ;
  onco:technologies <https://onco.cc/technologies/hipec/> ;
  onco:drugs <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/leucovorin/> ;
  onco:institutions <https://onco.cc/institutions/nki/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-surgery-radiation-innovation/>, <https://onco.cc/bottlenecks/b-care-fragmentation/> ;
  onco:journals <https://onco.cc/journals/jco/> .
