# OnCo record paper-yu-acquired-resistance-rebiopsy-egfr-ccr-2013 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-yu-acquired-resistance-rebiopsy-egfr-ccr-2013/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-yu-acquired-resistance-rebiopsy-egfr-ccr-2013" ;
  schema:name "Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers"@en ;
  schema:description "Rebiopsying 155 patients whose targeted pill had stopped working put numbers on how they escape: about two thirds by one mutation, a few by making extra copies of another receptor, and a few by turning into a different kind of cancer altogether."@en ;
  schema:url <https://onco.cc/key-papers/paper-yu-acquired-resistance-rebiopsy-egfr-ccr-2013/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1158/1078-0432.CCR-12-2246>, <https://pubmed.ncbi.nlm.nih.gov/23470965/> ;
  schema:sameAs <https://doi.org/10.1158/1078-0432.CCR-12-2246> ;
  schema:datePublished "2013"^^xsd:gYear ;
  schema:author "Yu HA, Arcila ME, Rekhtman N, et al." ;
  onco:related <https://onco.cc/biomarkers/egfr-t790m/>, <https://onco.cc/biomarkers/met-amplification-readout/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/sclc/> ;
  onco:technologies <https://onco.cc/technologies/cytogenetics-fish/>, <https://onco.cc/technologies/cgp/> ;
  onco:targets <https://onco.cc/targets/egfr/>, <https://onco.cc/targets/met/>, <https://onco.cc/targets/her2/> ;
  onco:drugs <https://onco.cc/drugs/erlotinib/>, <https://onco.cc/drugs/gefitinib/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/> ;
  onco:pathways <https://onco.cc/pathways/resistance-routes-map/>, <https://onco.cc/pathways/rtk-activation/>, <https://onco.cc/pathways/lineage-plasticity-neuroendocrine/> ;
  onco:terms <https://onco.cc/terms/resistance/>, <https://onco.cc/terms/histologic-transformation/>, <https://onco.cc/terms/met-amplification/>, <https://onco.cc/terms/biopsy/> ;
  onco:people <https://onco.cc/people/gregory-riely/> ;
  onco:journals <https://onco.cc/journals/clinical-cancer-research/> .