# OnCo record paper-zhang-lung-cancer-never-smokers-nat-genet-2021 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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<https://onco.cc/key-papers/paper-zhang-lung-cancer-never-smokers-nat-genet-2021/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-zhang-lung-cancer-never-smokers-nat-genet-2021" ;
  schema:name "Genomic and evolutionary classification of lung cancer in never smokers"@en ;
  schema:description "The Sherlock-Lung study sequenced 232 lung cancers from people who never smoked and found three distinct types, none of them carrying the tobacco damage signature. One type appears to begin decades before it is diagnosed."@en ;
  schema:url <https://onco.cc/key-papers/paper-zhang-lung-cancer-never-smokers-nat-genet-2021/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41588-021-00920-0>, <https://pubmed.ncbi.nlm.nih.gov/34493867/>, <https://dceg.cancer.gov/research/what-we-study/sherlock-lung> ;
  onco:tag "lung-evidence" ;
  schema:sameAs <https://doi.org/10.1038/s41588-021-00920-0> ;
  schema:datePublished "2021"^^xsd:gYear ;
  schema:author "Zhang T, Joubert P, Ansari-Pour N, et al." ;
  onco:related <https://onco.cc/key-papers/paper-hill-lung-adenocarcinoma-air-pollutants-nature-2023/>, <https://onco.cc/key-papers/paper-jamal-hanjani-tracerx-evolution-nsclc-nejm-2017/> ;
  onco:cancers <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/lung-adenocarcinoma/> ;
  onco:sections <https://onco.cc/fronts/early-detection/>, <https://onco.cc/fronts/diagnostics/> ;
  onco:technologies <https://onco.cc/technologies/wes-wgs/> ;
  onco:targets <https://onco.cc/targets/egfr/>, <https://onco.cc/targets/kras/> ;
  onco:institutions <https://onco.cc/institutions/nci/> ;
  onco:terms <https://onco.cc/pathways/clonal-evolution/>, <https://onco.cc/terms/driver-mutation/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-early-detection/>, <https://onco.cc/bottlenecks/b-tumor-heterogeneity/>, <https://onco.cc/bottlenecks/b-rare-cancers/> ;
  onco:journals <https://onco.cc/journals/nature-genetics/> .