# OnCo record paper-zuma-5-axi-cel-indolent-lymphoma-lancet-oncol-2022 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-zuma-5-axi-cel-indolent-lymphoma-lancet-oncol-2022/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-zuma-5-axi-cel-indolent-lymphoma-lancet-oncol-2022" ;
  schema:name "Axicabtagene ciloleucel in relapsed or refractory indolent non-Hodgkin lymphoma (ZUMA-5): a single-arm, multicentre, phase 2 trial"@en ;
  schema:alternateName "ZUMA-5"@en, "Jacobson 2022"@en ;
  schema:description "The first CAR-T trial in slow-growing lymphoma: more than nine in ten responded and three quarters went into complete remission, with severe neurological events in about one in five."@en ;
  schema:url <https://onco.cc/key-papers/paper-zuma-5-axi-cel-indolent-lymphoma-lancet-oncol-2022/> ;
  schema:dateModified "2026-10-01"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/S1470-2045(21)00591-X>, <https://pubmed.ncbi.nlm.nih.gov/34895487/>, <https://europepmc.org/article/MED/34895487> ;
  onco:tag "lymphoma-evidence" ;
  schema:sameAs <https://doi.org/10.1016/S1470-2045(21)00591-X> ;
  schema:datePublished "2022"^^xsd:gYear ;
  schema:author "Jacobson CA, Chavez JC, Sehgal AR, et al." ;
  onco:related <https://onco.cc/roadmaps/lymphoma-roadmap/> ;
  onco:cancers <https://onco.cc/cancers/follicular-lymphoma/>, <https://onco.cc/cancers/marginal-zone-lymphoma/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:sections <https://onco.cc/fronts/cell-therapy/> ;
  onco:technologies <https://onco.cc/technologies/car-t/> ;
  onco:targets <https://onco.cc/targets/cd19/> ;
  onco:drugs <https://onco.cc/drugs/axicabtagene-ciloleucel/>, <https://onco.cc/drugs/cyclophosphamide/>, <https://onco.cc/drugs/fludarabine/> ;
  onco:companies <https://onco.cc/companies/gilead/> ;
  onco:terms <https://onco.cc/terms/crs/>, <https://onco.cc/terms/icans/>, <https://onco.cc/terms/lymphodepletion/>, <https://onco.cc/terms/lugano-classification/> ;
  onco:trials <https://onco.cc/trials/zuma-5/>, <https://onco.cc/trials/elara/> ;
  onco:people <https://onco.cc/people/caron-jacobson/>, <https://onco.cc/people/gilles-salles/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-manufacturing-cell-therapy/>, <https://onco.cc/bottlenecks/b-toxicity-qol/> ;
  onco:journals <https://onco.cc/journals/lancet-oncology/> .