# OnCo record paper-zuma-7-axi-cel-second-line-nejm-2022 (paper). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/key-papers/paper-zuma-7-axi-cel-second-line-nejm-2022/>
  a schema:ScholarlyArticle ;
  onco:kind "paper" ;
  schema:identifier "paper-zuma-7-axi-cel-second-line-nejm-2022" ;
  schema:name "ZUMA-7: axi-cel CAR-T instead of salvage chemotherapy and transplant for large B-cell lymphoma that relapses early"@en ;
  schema:description "For lymphoma that came back within a year, going straight to CAR-T beat the decades-old chemotherapy-then-transplant approach, and later improved survival."@en ;
  schema:url <https://onco.cc/key-papers/paper-zuma-7-axi-cel-second-line-nejm-2022/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2116133>, <https://doi.org/10.1056/NEJMoa2301665>, <https://clinicaltrials.gov/study/NCT03391466> ;
  schema:sameAs <https://doi.org/10.1056/NEJMoa2116133> ;
  schema:datePublished "2022"^^xsd:gYear ;
  schema:author "Locke FL, Miklos DB, Jacobson CA, et al." ;
  onco:related <https://onco.cc/pairings/car-t-before-transplant-lbcl/>, <https://onco.cc/key-papers/paper-transform-liso-cel-lancet-2022/>, <https://onco.cc/roadmaps/lymphoma-roadmap/>, <https://onco.cc/key-papers/paper-belinda-tisagenlecleucel-second-line-nejm-2022/>, <https://onco.cc/ideas/lymphoma-ev-manufacturing-time-as-a-trial-endpoint/> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/> ;
  onco:technologies <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/autologous-stem-cell-transplant/> ;
  onco:targets <https://onco.cc/targets/cd19/> ;
  onco:drugs <https://onco.cc/drugs/axicabtagene-ciloleucel/> ;
  onco:companies <https://onco.cc/companies/gilead/> ;
  onco:institutions <https://onco.cc/institutions/moffitt/> ;
  onco:terms <https://onco.cc/terms/efs/>, <https://onco.cc/terms/os/>, <https://onco.cc/terms/crs/>, <https://onco.cc/terms/icans/> ;
  onco:trials <https://onco.cc/trials/zuma-7/>, <https://onco.cc/trials/transform/>, <https://onco.cc/trials/belinda/> ;
  onco:people <https://onco.cc/people/frederick-locke/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-manufacturing-cell-therapy/>, <https://onco.cc/bottlenecks/b-global-access/> ;
  onco:journals <https://onco.cc/journals/nejm/> .