# OnCo record pbrm1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/pbrm1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "pbrm1" ;
  schema:name "PBRM1"@en ;
  schema:alternateName "polybromo 1"@en, "BAF180"@en, "PB1"@en, "SMARCH1"@en, "PBRM1" ;
  schema:description "PBRM1 (polybromo 1) is a protein that switches other genes on and off. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Renal cell carcinoma, Skin cancer, Biliary tract cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/pbrm1/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:30064>, <https://www.uniprot.org/uniprotkb/Q86U86/entry>, <https://www.ncbi.nlm.nih.gov/gene/55193>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000163939> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:30064>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000163939>, <https://www.uniprot.org/uniprotkb/Q86U86/entry>, <https://www.ncbi.nlm.nih.gov/gene/55193> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/biliary-tract-cancer/>, <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/mesothelioma/>, <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/gastric/> .