# OnCo record pecoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/pecoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "pecoma" ;
  schema:name "Perivascular epithelioid cell tumour (PEComa)"@en ;
  schema:alternateName "PEComa"@en, "Malignant PEComa"@en, "Angiomyolipoma and lymphangioleiomyomatosis (PEComa family)"@en ;
  schema:description "PEComa is a rare tumour of cells that sit around blood vessels and share features of muscle and pigment cells. Most are benign, but malignant ones spread and resist chemotherapy. They usually have lost the TSC1 or TSC2 brake on the growth signal mTOR, and in 2021 the mTOR blocker nab-sirolimus became the first approved treatment."@en ;
  schema:url <https://onco.cc/cancers/pecoma/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Perivascular_epithelioid_cell_tumour> ;
  schema:citation <https://en.wikipedia.org/wiki/Perivascular_epithelioid_cell_tumour> ;
  onco:tag "subtype-page" ;
  onco:related <https://onco.cc/cancers/uterine-sarcoma/>, <https://onco.cc/cancers/retroperitoneal-sarcoma/> ;
  onco:pipeline <https://onco.cc/drugs/sirolimus-albumin-bound/>, <https://onco.cc/trials/nct05103358/>, <https://onco.cc/trials/ampect/> ;
  onco:standardOfCare <https://onco.cc/technologies/limb-salvage-surgery/>, <https://onco.cc/technologies/active-surveillance/>, <https://onco.cc/drugs/sirolimus-albumin-bound/>, <https://onco.cc/trials/ampect/>, <https://onco.cc/drugs/everolimus/>, <https://onco.cc/drugs/temsirolimus/>, <https://onco.cc/targets/mtor/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/trials/nct05103358/> .