# OnCo record pegfilgrastim (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/pegfilgrastim/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "pegfilgrastim" ;
  schema:name "Pegfilgrastim"@en ;
  schema:alternateName "Fulphila (pegfilgrastim-jmdb)"@en, "Udenyca (pegfilgrastim-cbqv)"@en, "Ziextenzo (pegfilgrastim-bmez)"@en, "Nyvepria (pegfilgrastim-apgf)"@en, "Fylnetra"@en, "Stimufend"@en, "Undencyca"@en, "Neulasta Onpro on-body injector"@en, "Neulasta" ;
  schema:description "Pegfilgrastim (Neulasta) is a long-acting form of the growth factor G-CSF, given once per chemotherapy cycle to speed white cell recovery and prevent febrile neutropenia; one dose replaces about eleven daily filgrastim injections. Biosimilars have been sold since 2018 and the Onpro on-body injector delivers it automatically the day after chemotherapy; bone pain is the main side effect."@en ;
  schema:url <https://onco.cc/drugs/pegfilgrastim/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Pegfilgrastim> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=pegfilgrastim>, <https://www.cancer.gov/about-cancer/treatment/drugs/pegfilgrastim>, <https://www.ema.europa.eu/en/medicines/human/EPAR/neulasta> ;
  onco:status "approved" ;
  onco:tag "nci-list", "supportive" ;
  onco:modality "Pegylated recombinant granulocyte colony-stimulating factor" ;
  onco:approval "US 2002: Decrease in febrile neutropenia in non-myeloid malignancies on myelosuppressive chemotherapy (acute radiation syndrome added 2015)", "US 2018: First biosimilars (Fulphila, Udenyca); further biosimilars 2019 onwards", "EU 2002: Reduction in duration of neutropenia and febrile neutropenia after cytotoxic chemotherapy (Neulasta); biosimilars from 2018" ;
  onco:related <https://onco.cc/drugs/filgrastim/> ;
  onco:technologies <https://onco.cc/technologies/g-csf-growth-factors/> ;
  onco:companies <https://onco.cc/companies/amgen/>, <https://onco.cc/companies/sandoz/>, <https://onco.cc/companies/eurofarma/> ;
  onco:trials <https://onco.cc/trials/nct06690775/> .